Top AI Startups in the US [2025]: Emerging Leaders in GenAI, LLMs & Automation

We’ve curated a list of the top 50 US AI startups to watch in 2025.

From infrastructure breakthroughs and developer platforms to conversational agents, AI hardware, and generative media, these companies are pushing the boundaries of what’s possible with artificial intelligence.

Let’s dive in.

1. Inflection AI

Industry: AI / Generative AI / Conversational Agents

Inflection AI builds enterprise-grade large language models, originally known for its empathetic chatbot Pi, now pivoted to providing customized generative AI models and APIs to businesses.

Location: Palo Alto, CA, USA
Founded: 2022
Last Funding Round: $1.3B (Series Unknown), June 2023
Total Funding: $1.525B
Valuation: ~$4B post-money, June 2023
Number of Users: Tens of millions of Pi users; current enterprise deployments not publicly disclosed
Growth Rate: After strategic shift in March 2024 when co-founders and much of the team joined Microsoft, Inflection refocused on enterprise AI with estimated ~$15.9M revenue and ~60%+ employee growth in 2025

Key Features

Customizable LLMs, enterprise AI APIs, generative AI model fine-tuning, conversational agents, scalable infrastructure, real-time enterprise deployment

2. Cognition AI

Industry: AI / Autonomous Coding Agents / Developer Tools

Cognition AI develops Devin, an autonomous AI software engineer built to plan, write, debug, test, and deploy code end-to-end within a sandboxed environment using reinforcement learning and LLMs.

Location: San Francisco, CA, USA (also New York office)
Founded: November 2023
Last Funding Round: Venture funding (post-Series A extension), April 2025 (hundreds of millions raised)
Total Funding: ~$196M (including $21M Series A + $175M extension)
Valuation: ~$4B as of March 2025
Number of Users: Enterprise engineering teams; acquired Windsurf bringing $82M ARR and 350+ enterprise customers
Growth Rate: Rapid growth with nearly doubling valuation within a year, integrating Windsurf acquisition and growing revenue footprint

Key Features

Full-stack autonomous coding assistant, reinforcement-learning powered LLM, sandboxed environment (shell, editor, browser), multi-step reasoning, bug detection & automated fixes, project-level execution, Windsurf IDE integration

3. Together AI

Industry: AI / Cloud Infrastructure / Open Source AI Platform

Together AI offers an AI Acceleration Cloud platform enabling developers and enterprises to train, fine-tune, and run inference on open-source generative AI models with enterprise-grade performance and scalability.

Location: San Francisco, California, USA
Founded: 2022
Last Funding Round: Series B, $305M, February 2025
Total Funding: ~$411M ($106M Series A + $305M Series B)
Valuation: $3.3B as of February 2025
Number of Users: Over 450,000 AI developers and enterprises including Salesforce, Zoom, SK Telecom, Washington Post
Growth Rate: Revenue surged from ~$30M (Feb 2024) to over $100M by early 2025, doubling valuation in under a year

Key Features

Support for 200+ open-source models (chat, image, audio, code, embeddings), proprietary inference engine with FlashAttention & quantization, fine-tuning and training pipelines, VPC/on-prem/cloud deployment, GPU infra on NVIDIA Blackwell, API-first platform, open methods (RedPajama dataset, model tools), high-performance low-latency inference

4. Celestial AI

Industry: AI / Optical Interconnect / Data Center Infrastructure

Celestial AI develops Photonic Fabric™, a silicon-photonic interconnect platform that uses light to link compute and memory at chip, package, and rack scales—enabling high-bandwidth, low-latency, and energy-efficient AI infrastructure.

Location: Santa Clara, California, USA
Founded: 2020
Last Funding Round: Series C1, $250M, March 2025
Total Funding: $515M+
Valuation: ~$2.5B post-money
Number of Users: Hyperscaler deployments (Amazon, Google, Microsoft, Meta) and IP licensing to chip/packaging partners (numbers undisclosed)
Growth Rate: Surpassed $175M Series C in 2024, raised $250M C1 in 2025, scaling hyperscaler adoption and expanding supply chain readiness, deepening investor base (AMD, BlackRock, Fidelity, Tiger Global, Koch, Temasek)

Key Features

Photonic Fabric interconnect, chip-package-rack scale connectivity, TB/s bandwidth, ultra-low latency, in-network-memory, up to 10× energy reduction, compute/memory disaggregation, industry-standard 2.5D packaging compatibility, photonic light engines (via POET Technologies)

5. Pathos

Industry: AI / Biotechnology / Oncology Drug Discovery

Pathos AI is a clinical-stage biotech company building a multimodal AI foundation model (PathOS™) that integrates clinical, molecular, and imaging data to accelerate oncology drug development, optimizing trial design and patient selection.

Location: Chicago, Illinois, USA
Founded: 2020 (spun out of Tempus AI)
Last Funding Round: Series D, $365M, May 2025
Total Funding: ~$467–469M (including $62M Series C + $365M Series D)
Valuation: ~$1.6B post-money after Series D
Number of Users: Biopharma partners and clinical teams (figures undisclosed)
Growth Rate: Accelerated growth with late-stage asset acquisitions, platform scaling, leadership transition with new CEO Iker Huerga, strategic collaborations with Tempus and AstraZeneca

Key Features

Multimodal AI foundation model (PathOS), integration of pathology/molecular/clinical imaging data, trial optimization, causal AI for biomarker discovery, pharma collaborations, clinical-stage drug pipeline acceleration

6. Magic

Industry: AI / Generative AI / Developer Tools

Magic builds foundation models optimized for programming, creating an AI "colleague" capable of writing, debugging, reviewing, and planning code autonomously using ultra-long context LTM networks.

Location: San Francisco, California, USA
Founded: 2022
Last Funding Round: $320M, Series C, August 2024
Total Funding: ~$465M
Valuation: ~$1.58B in May 2025
Number of Users: Not publicly disclosed
Growth Rate: Revenue reached $2M in 2023; consistent revenue growth since launch in 2022, reflecting adoption across industries

Key Features

LTM long-term memory networks (up to 100M-token context), internal LTM-2-mini model, collaboration with Google Cloud for Magic-G4/H100 and Magic-G5/Blackwell supercomputers, ultra-long context processing, scalable GPU deployment, roadmap toward AGI-level coding assistant

7. Skild AI

Industry: AI / Robotics / Foundation Models

Skild AI builds a general-purpose "brain" for robots (quadrupeds, humanoids, etc.) enabling navigation, manipulation, and versatile task execution across environments without task-specific programming.

Location: Pittsburgh, PA, USA (also Bay Area presence)
Founded: 2023
Last Funding Round: Series A, $300M, July 2024
Total Funding: $300M
Valuation: ~$1.5B post-Series A
Number of Users: Not publicly disclosed (piloting with diverse robot OEMs)
Growth Rate: Rapid scale-up; in talks for $500M SoftBank investment valuing company near $4B

Key Features

Foundation model for robotics, emergent manipulation/navigation skills, trained on 1,000× more data than competitors, adaptable across robotic platforms, plug-and-play capability, strong investor backing (Lightspeed, Coatue, SoftBank, Bezos Expeditions)

8. Decagon

Industry: AI-powered Customer Support

Decagon develops AI agents that automate and resolve customer support inquiries across chat, email, and voice channels, enhancing enterprise customer experience.

Location: San Francisco, CA, USA
Founded: 2023
Last Funding Round: Series C, $131M, June 2025
Total Funding: $266M
Valuation: ~$1.5B
Number of Users: Trusted by Bilt, ClassPass, Duolingo, Eventbrite, Rippling, and Vanta
Growth Rate: Reached seven-figure ARR with just 2 employees by June 2024; scaled to 55 employees by February 2025

Key Features

Omnichannel AI support (chat, email, voice), agentic AI with real-time actions, natural language instructions for agent behavior, seamless integrations with enterprise systems, continuous learning loops, customizable business logic via Agent Operating Procedures (AOPs)

9. SpreeAI

Industry: AI / Fashion Tech / Retail Personalization

SpreeAI provides photorealistic virtual try-on solutions and AI-driven sizing for fashion retailers, enabling shoppers to visualize clothing on their own image with 99% sizing accuracy, reducing returns and boosting conversions.

Location: United States (HQ in Incline Village, NV)
Founded: January 2023 (emerged from stealth in 2024)
Last Funding Round: Series B, $15M (Nov 2023); undisclosed growth round led by The Davidson Group, May 2025
Total Funding: ~$15M disclosed
Valuation: ~$1.5B as of May 2025
Number of Users: Retail partnerships with major brands
Growth Rate: Rapid traction through global retail collaborations, partnerships with MIT, Carnegie Mellon, CFDA, and measurable sustainability impact through reduced returns

Key Features

Photorealistic virtual try-on, 99% accurate AI sizing, virtual wardrobe, AI stylist features, retailer dashboard Protea, seamless e-commerce integration, reduced returns for sustainability

10.Windsurf

Industry: AI-powered Coding Tools

Windsurf is an AI-native IDE designed to streamline software development with agentic AI workflows, enabling developers to generate, refactor, and deploy code more efficiently.

Location: Mountain View, CA, USA
Founded: 2021
Last Funding Round: Series C, $150M, September 2024
Total Funding: $244.7M
Valuation: ~$1.3B
Number of Users: Over 1M active developers
Growth Rate: Achieved $40M ARR by February 2025

Key Features

Cascade AI agent, Supercomplete autocompletion, multi-agent code refactoring, one-click deployment, real-time previews, Figma-to-code generation, integrations with Slack, Stripe, and GitHub, extensible plugin ecosystem

11. Snorkel AI

Industry: AI / Data Development / ML Infrastructure

Snorkel AI provides a data development platform that helps enterprises build, label, evaluate, and tune AI/ML models at scale using programmatic weak supervision, expert-assisted datasets, and evaluation workflows—particularly for unstructured data like text, documents, logs, and images.

Location: Redwood City, California, USA
Founded: 2019
Last Funding Round: Series D, $100M, May 2025 (led by Addition with Greylock, Lightspeed, Prosperity7 Ventures)
Total Funding: $237M across six rounds
Valuation: ~$1.3B (May 2025)
Number of Users: Fortune 500 enterprises and U.S. federal agencies (not publicly disclosed)
Growth Rate: Triple-digit customer growth in 2022; recent platform momentum driving 40%+ cost savings; accelerated adoption of Snorkel Evaluate and Expert Data offerings

Key Features

Programmatic weak supervision labeling, labeling functions, Snorkel Flow platform, Snorkel Evaluate, Expert Data-as-a-Service, end-to-end data development, model tuning and evaluation, workflow orchestration, domain-specific datasets, analytics and error analysis

12. DevRev

Industry: AI / Enterprise Software / CRM

DevRev offers an AI-native business operating system (AgentOS) that unifies customer support, product development, and engineering teams through a conversational interface powered by a knowledge graph and AI agents.

Location: Palo Alto, California, USA
Founded: October 2020 (by Dheeraj Pandey and Manoj Agarwal)
Last Funding Round: Series A, $100.8M, August 2024
Total Funding: ~$186M (seed + Series A extensions)
Valuation: ~$1.15B (post-Series A)
Number of Users: 1,000+ customers including SaaS unicorns, enterprise banks, AI chip designers, startups, and growth-stage companies
Growth Rate: Rapid expansion; named a top 20 U.S. startup employer in 2025 by Forbes; strong traction in AI-native CRM globally

Key Features

Conversational AI agents for support/product/engineering, patented Airdrop tech for ingesting legacy data, unified enterprise knowledge graph, lightning-fast analytics, conversational search, SaaS-tailored AI-native CRM apps, seamless integrations

13. Statsig

Industry: AI / Product Development / Experimentation Platform

Statsig provides a unified experimentation and product analytics platform combining feature flags, A/B testing, product analytics, session replay, and web analytics to enable engineering teams to make data-driven product decisions and optimize rollouts.

Location: Bellevue, Washington, USA
Founded: February 2021
Last Funding Round: Series C, $100M, May 2025
Total Funding: ~$153M
Valuation: ~$1.1B (post-Series C unicorn)
Number of Users: Thousands, including Notion, Microsoft, Brex, Atlassian, EA, Flipkart
Growth Rate: ARR grew to $40M by mid-2025; headcount scaled from ~31 (2022) to ~140 (2025), projected ~175–190 by 2026

Key Features

A/B testing and experimentation, feature flag management, session replay, web analytics, warehouse-native integration, scalable stats engine, real-time analytics, low-latency evaluation (<1ms), unified platform for product teams

14. Truveta

Industry: AI / HealthTech / Medical Data

Truveta aggregates de-identified EHR data from U.S. hospital partners to create comprehensive datasets and AI models that support drug discovery, clinical research, genomics, and population health studies.

Location: Bellevue, Washington, USA
Founded: 2020
Last Funding Round: Series C, $320M, January 2025 (led by Regeneron, Illumina, and 17 health systems)
Total Funding: ~$515M (four rounds)
Valuation: >$1B (post-Series C unicorn)
Number of Users: Data covering over 120M patients across U.S. health systems
Growth Rate: Rapid platform scaling; 387 employees by 2025; ~$72M annual revenue

Key Features

Regulatory-grade de-identified EHR data, daily clinical data updates, Truveta Language Model for multimodal normalization, large-scale genome/phenotype linkage (Truveta Genome Project targeting 10M exomes), AI analytics for life sciences and public health

15. EvenUp

Industry: AI / Legal Tech / Case Management

EvenUp delivers an AI-powered claims intelligence platform for personal injury law firms, automating drafting, case evaluation, and negotiation preparation using a model trained on legal and medical data.

Location: San Francisco, CA, USA (with office in Toronto, Canada)
Founded: 2019
Last Funding Round: Series D, $135M, October 2024
Total Funding: $235M
Valuation: >$1B (unicorn status)
Number of Users: 1,000+ personal injury law firms across the U.S.
Growth Rate: Revenue doubled year-over-year; workforce scaled from ~100 to ~500 employees in two years; expanded offices and product suite in 2025

Key Features

AI-based document drafting, claims intelligence trained on legal/medical data, case evaluation workflows, missing-doc detection, settlement repository, real-time Q&A assistant, analytics dashboards, SOC2/HIPAA compliance

16. World Labs

Industry: AI / Spatial Intelligence / Generative 3D Modeling

World Labs is building Large World Models (LWMs) that enable AI to perceive, generate, and interact with 3D environments—both virtual and real—pushing spatial intelligence beyond 2D pixels.

Location: San Francisco, CA, USA
Founded: 2024 (by Fei-Fei Li, Justin Johnson, Christoph Lassner, Ben Mildenhall)
Last Funding Round: $230M venture round, September 2024 (led by Andreessen Horowitz, NEA, Radical Ventures, with Nvidia NVentures, Marc Benioff, Ashton Kutcher, Reid Hoffman, Eric Schmidt)
Total Funding: $230M
Valuation: >$1B (as of latest round)
Number of Users: Not publicly disclosed; 11–50 employees at launch
Growth Rate: Achieved unicorn status within months of founding; lean team with strong investor backing

Key Features

Generative 3D world models, spatial intelligence foundation models, image-to-3D conversion, real-time explorable browser-based scenes, physics-aware semantics, interactive lighting and camera controls

17. Typeface

Industry: AI / Enterprise Software / Content Creation

Typeface provides a generative AI platform that helps enterprises create personalized, on-brand content at scale, embedding AI tools directly into business workflows for marketing, product, sales, and HR.

Location: Palo Alto, California, USA
Founded: 2022
Last Funding Round: Series B, $100M, June 2023
Total Funding: $165M
Valuation: $1B
Number of Users: Fortune 500 enterprises across multiple departments
Growth Rate: Rapid adoption in enterprise markets; expanding global presence

Key Features

Brand Hub for dynamic brand guidelines, Arc Agents for campaign automation, collaborative Spaces, multimodal AI (text, image, video, audio), Salesforce Marketing GPT integration, advanced video tech from TensorTour acquisition, enterprise security/compliance, customizable API workflows

18. Speak

Industry: AI / Language Learning

Speak is an AI-driven language learning platform focused on speaking practice, offering real-time conversation with an AI tutor and personalized feedback on pronunciation, grammar, and vocabulary.

Location: San Francisco, CA, USA
Founded: 2016
Last Funding Round: Series C, $78M, December 2024
Total Funding: $152M
Valuation: $1B
Number of Users: 10M+ users across 40+ countries
Growth Rate: User base doubling annually for the past five years

Key Features

Real-time speech recognition, conversational lessons, pronunciation/grammar/vocabulary feedback, multilingual support (English, Spanish, French, German, Italian, Japanese, Chinese), mobile app, subscription pricing

19. Reka AI

Industry: AI / Multimodal LLMs for Enterprise

Reka AI develops highly efficient multimodal foundation models (e.g., Reka Flash, Reka Vision) that process text, images, video, and audio with low-cost inference, making them accessible for enterprise deployment.

Location: Sunnyvale, California, USA (globally distributed team)
Founded: 2022 (by former Google, Meta, and DeepMind researchers)
Last Funding Round: Series B, $110M (from Nvidia and Snowflake), July 2025
Total Funding: ~$160M (including $50M Series A in 2023)
Valuation: ~$1B (July 2025, tripled from ~$300M in 2023)
Number of Users: Enterprise/developer platform model (not disclosed)
Growth Rate: Employee count grew from ~20 to ~50 in past year; rapid scaling of models and infrastructure

Key Features

Reka Flash multimodal 21B model, Reka Flash 3.1 with near-lossless quantization, Reka Vision for visual QA and search, Reka Research agentic QA tool, cost-efficient inference pipelines, customizable enterprise tools, low-compute deployment

20. Augment Code

Industry: AI / Developer Productivity / Coding Assistant

Augment Code provides AI-powered developer tools with a proprietary context engine and autonomous agents to deliver project-aware code suggestions, debugging, documentation, and command execution across large codebases.

Location: Palo Alto, California, USA
Founded: 2022
Last Funding Round: Series B, $227M, April 2024
Total Funding: $252M
Valuation: ~$977M (post-money, April 2024)
Number of Users: Not publicly disclosed
Growth Rate: Rapid adoption; workforce scaling; reported “70% win rate” vs GitHub Copilot; strong developer traction

Key Features

200k-token context window, Augment Agent autonomous AI agents, personalized Memory, deep codebase understanding, multimodal inputs (screenshots, Figma), IDE integration (VS Code, JetBrains, Vim/Neovim), SOC2 compliance, real-time collaboration, automated refactoring, debugging, documentation support

21. Harmonic

Industry: AI / Mathematical Superintelligence

Harmonic is developing Mathematical Superintelligence (MSI), an AI framework rooted in mathematics to eliminate hallucinations and ensure accuracy in reasoning and output.

Location: Palo Alto, California, USA
Founded: 2023
Last Funding Round: Series B, $175M, July 2025
Total Funding: $175M
Valuation: ~$900M (post-money)
Number of Users: Not publicly disclosed
Growth Rate: Not publicly disclosed

Key Features

Mathematical reasoning, hallucination-free AI models, advanced accuracy-first architecture, new mathematical foundations for next-generation AI

22. Tractian

Industry: AI / Industrial IoT / Predictive Maintenance

Tractian provides an AI-driven Industrial Copilot combining sensors, edge computing, and predictive AI models to monitor industrial assets, prevent downtime, and increase maintenance efficiency.

Location: Atlanta, GA, USA (offices in São Paulo and Mexico City)
Founded: 2019
Last Funding Round: Series C, $120M, December 2024
Total Funding: ~$180M
Valuation: ~$700M
Number of Users: 500+ customers across 1,000 industrial plants (e.g., John Deere, Bosch, Embraer, Hyundai)
Growth Rate: Rapid expansion; 200+ R&D engineers; filed 12 patents in 2024; supports ~5% of global industrial GDP; ~$6,000 annual savings per machine

Key Features

Custom IoT vibration/temperature sensors, edge computing, AI-driven machine “fingerprint” analysis, integrated CMMS, automated work-order management, real-time diagnostics and alerts, geolocation tracking, OEE optimization, AI-assisted maintenance

23. Hebbia

Industry: AI / Document Intelligence

Hebbia builds AI-powered research tools that allow financial and legal professionals to analyze large volumes of documents and answer complex queries in natural language.

Location: New York City, NY, USA
Founded: 2020
Last Funding Round: Series B, $130M, July 2024
Total Funding: $160M+
Valuation: ~$700M
Number of Users: ~30% of the 50 largest global asset managers
Growth Rate: 15× revenue growth in the past 18 months

Key Features

AI-driven document search and analysis, natural language query interface, support for PDFs, spreadsheets, slides, workflow integrations, scalable AI agents, process-oriented and persistent AI models

24. webAI

Industry: AI / Distributed Infrastructure

webAI provides a privacy-focused AI platform enabling enterprises to deploy and manage AI models locally, reducing reliance on cloud providers while ensuring stronger data security.

Location: Austin, TX, USA
Founded: 2019
Last Funding Round: Series A, $60M, September 2024
Total Funding: $60M
Valuation: ~$700M
Number of Users: ~113 employees (June 2025)
Growth Rate: $15M annual revenue (June 2025); scaling rapidly

Key Features

Localized AI deployment, on-device inference, reduced latency, integration with existing hardware, enterprise-grade privacy and security, scalable distributed AI infrastructure, Companion on-device AI assistant

25. Tennr

Industry: AI / Healthcare Automation

Tennr uses AI to automate patient referral processing, extracting data from faxes, emails, and e-portals with a proprietary vision-language model to streamline healthcare operations.

Location: New York, NY, USA
Founded: 2021
Last Funding Round: Series C, $101M, June 2025
Total Funding: $162M
Valuation: ~$605M
Number of Users: Hundreds of healthcare organizations, thousands of providers
Growth Rate: 3× revenue growth since October 2024

Key Features

RaeLM vision-language model, automated referral intake, payer checks, denial prediction, benefits/eligibility extraction, billing automation, authorization review, phone call parsing via T3, real-time tracking via Tennr Network

26. Enfabrica

Industry: AI Infrastructure / Networking Silicon

Enfabrica develops high-performance networking silicon and software (Accelerated Compute Fabric – ACF) designed to optimize GPU and accelerator interconnects for large-scale AI and compute clusters.

Location: Mountain View, CA, USA (R&D hubs in Atlanta and Hyderabad)
Founded: 2020
Last Funding Round: Series C, $115M, November 2024 (Spark Capital, Arm, Cisco, Samsung Catalyst, VentureTech Alliance)
Total Funding: ~$240M
Valuation: ~$590M
Number of Users: Not publicly disclosed (commercial launch Q1 2025)
Growth Rate: Produced 3.2 Tbps SuperNIC chip; scaling pilot deployments and expanding global R&D

Key Features

3.2 Tbps ACF SuperNIC, multi-port 800-Gigabit Ethernet, multipath fault-tolerant networking, GPU/CPU/CXL memory integration, scalable up to ~500k accelerators, software-defined RDMA fabric

27. Reflection AI

Industry: AI / Autonomous Coding Agents

Reflection AI builds “superhuman general agents” that autonomously write, debug, test, and deploy code by combining reinforcement learning with large language models.

Location: New York City, NY, USA (with offices in SF, Paris, and London)
Founded: 2024
Last Funding Round: Series A, $105M (plus $25M seed), March 2025
Total Funding: $130M
Valuation: ~$555M
Number of Users: Enterprise customers in finance, tech, and large engineering teams
Growth Rate: Post-money valuation rose from $100M (Aug 2024) to $555M (Mar 2025); rapid global hiring

Key Features

Autonomous coding agent API, code writing and debugging, automated testing and deployment, infrastructure management, workflow automation for engineering productivity

28. Rad AI

Industry: Healthcare AI / Radiology Workflow

Rad AI automates radiology report generation, helping clinicians reduce burnout, improve diagnostic accuracy, and streamline workflows across healthcare systems.

Location: San Francisco, CA, USA
Founded: 2018
Last Funding Round: Series C, $68M, May 2025
Total Funding: $140M+
Valuation: ~$525M
Number of Users: Deployed in one-third of U.S. health systems; used by 9 of the 10 largest U.S. radiology practices
Growth Rate: 8,710% revenue growth from 2020 to 2023; ranked #19 on Deloitte’s 2024 Technology Fast 500

Key Features

Generative AI report drafting, Omni Impressions for structured findings, EHR integration, real-time follow-up management, voice-enabled dictation, clinician burnout reduction, partnerships with Advocate Health, Memorial Hermann, Corewell Health, Atlantic Health

29. Sanas

Industry: AI / Speech Technology

Sanas develops real-time speech AI solutions including accent translation and noise cancellation, designed to make global communication more inclusive and effective.

Location: Palo Alto, California, USA
Founded: 2020
Last Funding Round: Series B, $65M, February 2025
Total Funding: $121M
Valuation: $500M+
Number of Users: Not publicly disclosed
Growth Rate: Global operations in 200+ territories

Key Features

Real-time accent translation, speech-to-speech AI, noise cancellation, omni-directional processing, enterprise-grade security, multilingual inclusivity tools

30. Captions

Industry: AI / Video Creation & Editing

Captions provides an AI-powered creative studio that allows anyone to produce professional-grade videos with automated editing, dubbing, and 3D avatar tools.

Location: New York City, NY, USA
Founded: 2021
Last Funding Round: Series C, $60M, 2024
Total Funding: $100M+
Valuation: ~$500M
Number of Users: 10M+ creators globally
Growth Rate: 3M+ videos created monthly

Key Features

AI-driven video editing, multilingual dubbing, 3D avatar generation, eye contact correction, noise removal, automatic captions, AI script generation, music and effects integration

31. OpenRouter

Industry: AI Infrastructure / Model Routing API

OpenRouter provides a unified API that routes queries to over 400 large language models, optimizing for cost, latency, uptime, and privacy across multiple providers.

Location: New York, NY, USA (fully remote team)
Founded: 2023
Last Funding Round: Seed + Series A, $40M, June 2025
Total Funding: $40M
Valuation: ~$500M (reported range $500M–$5B)
Number of Users: 1M+ developers; hundreds of enterprises (customers spent $8M on inference in May 2025)
Growth Rate: Inference spend grew ~10× (Oct 2024–May 2025); annualized revenue rose ~400% to $5M

Key Features

Unified API for 400+ LLMs, automatic prompt routing for price/performance, failover across 50+ cloud providers, unified billing with 5% fee, enterprise security (zero-logging default, global edge deploy), real-time model performance insights

32. Read AI

Industry: AI Productivity Tools

Read AI offers a productivity platform that automates meeting summaries, transcription, and insight extraction across email, chat, and calendars, helping teams collaborate more efficiently.

Location: Seattle, WA, USA
Founded: 2023
Last Funding Round: Series B, $50M, October 2024
Total Funding: $81M
Valuation: $450M
Number of Users: 100k+ new accounts weekly; used by 75% of Fortune 500
Growth Rate: 81% first-month retention; strong enterprise adoption

Key Features

Multi-platform meeting summaries (Zoom, Teams, Google Meet), real-time transcription, action item and sentiment detection, email thread summarization, Slack and Outlook integrations, cross-app Search Copilot, calendar sync, Zapier/webhook support, enterprise-grade security (SOC 2, HIPAA for Enterprise+)

33. Etched AI

Industry: AI / Semiconductor / Chip Design

Etched AI builds transformer-specific chips (Sohu) optimized for inference, aiming to outperform general-purpose GPUs in both efficiency and cost for large-scale AI workloads.

Location: Cupertino, CA, USA
Founded: 2022
Last Funding Round: Series A, $120M, June 2024
Total Funding: $120M
Valuation: $300M–$500M (estimated)
Number of Users: Not publicly disclosed (35-person team)
Growth Rate: Scaling chip design/fabrication in partnership with TSMC; strong investor interest

Key Features

Transformer-optimized ASIC (Sohu), fabricated on TSMC 4nm, supports major LLMs, up to 10× faster/cheaper than Nvidia Blackwell GPUs, eight-chip servers delivering 500k+ Llama-70B tokens/sec, cost-efficient inference hardware

34. CodaMetrix

Industry: AI / Healthcare / Revenue Cycle Management

CodaMetrix offers an AI-powered medical coding platform that automates translating clinical documentation into billing codes, reducing admin workload and improving hospital revenue cycle efficiency.

Location: Boston, MA, USA
Founded: 2019
Last Funding Round: Series B, $40M, March 2024
Total Funding: ~$110M
Valuation: ~$395M
Number of Users: 200+ hospitals, 50k+ providers
Growth Rate: Widespread adoption in leading health systems (Mass General Brigham, Mount Sinai, University of Colorado Medicine)

Key Features

Multi-specialty coding automation (radiology, pathology, surgery, GI, E&M), real-time EHR integration, longitudinal patient record views, AI-driven audit capabilities, reduced coding costs and denials, improved compliance and provider satisfaction

35. Luma AI

Industry: Generative AI / 3D Imaging / Video

Luma AI develops tools for photorealistic 3D capture, text-to-video generation, and advanced video editing, used by creators and enterprises in e-commerce, entertainment, and marketing.

Location: Palo Alto, CA, USA
Founded: 2021
Last Funding Round: Series C, $90M, December 2024
Total Funding: $182.8M
Valuation: ~$300M (as of January 2024)
Number of Users: 25M+ registered users
Growth Rate: Not publicly disclosed

Key Features

Dream Machine (text-to-video), Ray2 (video editing), Photon (3D scene capture), Modify Video (post-production tools), NeRF export, API integrations, enterprise support for creative workflows

36. Armada

Industry: Edge Computing / AI / Connectivity Infrastructure

Armada provides a full-stack mobile edge computing platform for AI and real-time data processing in remote or constrained environments. Deployments include the Galleon mobile data center, Commander platform, and EdgeAI applications.

Location: San Francisco, CA, USA (headquarters); R&D in Trivandrum, India
Founded: Late 2022
Last Funding Round: Series A, ~$55M, December 2023
Total Funding: ~$55M (PitchBook: $95M total)
Valuation: $250M
Number of Users: Enterprise infrastructure platform (not publicly disclosed)
Growth Rate: Rapid expansion; planning ~500 employees; ~307 employees as of mid-2025

Key Features

Full-stack mobile edge compute (Galleon), Starlink satellite connectivity, Commander Connect OS, EdgeAI apps (OpsInsight, OpsSafety), edge app marketplace, SOC2/ISO27001 compliance, real-time processing at remote sites

37. EvolutionaryScale

Industry: AI / Biotechnology / Protein Engineering

EvolutionaryScale builds protein-design LLMs (ESM3) that accelerate drug discovery, materials science, and environmental applications by generating novel proteins and biological systems.

Location: New York, NY, USA
Founded: 2023
Last Funding Round: Seed, $142M, June 2024
Total Funding: $142M
Valuation: ~$200M (seed valuation)
Number of Users: Not publicly disclosed; model available via AWS, NVIDIA, research API
Growth Rate: ~20–50 employees; rapid adoption with ESM3 launch; strategic partnerships with AWS & NVIDIA

Key Features

Transformer-based protein LLM (98B parameters), trained on 2.78B protein sequences; generative protein design; open-source small model; commercial access via AWS SageMaker, Bedrock, NVIDIA NIM; engineered fluorescent protein bypassing 500M years of evolution

38. Hume AI

Industry: Emotional AI / Multimodal AI / Voice AI

Hume AI develops empathic voice interfaces and emotional expression models for healthcare, customer service, and conversational AI applications.

Location: New York City, USA
Founded: 2021
Last Funding Round: Series B, $50M, March 2024
Total Funding: $65.9M
Valuation: $140M–$230M
Number of Users: Not publicly disclosed
Growth Rate: Not publicly disclosed

Key Features

EVI 3 speech-language model, Octave TTS, expression measurement APIs, conversational voice agents, empathic voice synthesis, customizable voice personalities, real-time emotion understanding, multimodal emotion analysis (voice, text, facial), Claude integration

39. Cortica

Industry: AI / Autonomous AI / Healthcare Services

Cortica develops autonomous AI technologies with brain-inspired, unsupervised learning for image and video understanding, and operates physician-led autism care centers in the U.S.

Location: San Diego, CA, USA
Founded: 2007
Last Funding Round: Strategic round, $80M, November 2024
Total Funding: ~$200M–$300M (Series C $60M in 2021, Series D extensions)
Valuation: Not publicly disclosed
Number of Users: 1,600+ employees; serves 10,000+ children annually across 23 centers
Growth Rate: ~750M annual revenue (est. 2025); doubling clinics; expansion of value-based payer contracts

Key Features

Autonomous AI with 300+ patents, cortex-mimicking image/video understanding, integrated autism care centers, sensorimotor/neurodevelopmental therapies, value-based care model, strategic acquisitions (Springtide, Melmed)

40. Encharge AI

Industry: Semiconductor / AI Hardware / Edge Computing

EnCharge AI builds analog in-memory computing chips for edge AI, integrating computation and memory on a single chip for high performance and low power consumption.

Location: Santa Clara, CA, USA
Founded: 2022
Last Funding Round: Series B, $100M, February 2025
Total Funding: Over $162.9M
Valuation: Not publicly disclosed
Number of Users: Enterprise clients in edge computing, consumer electronics, and defense
Growth Rate: Rapid development; government grants and strategic partnerships

Key Features

Analog in-memory computing, EN100 AI accelerator chip, M.2/PCIe form factors, up to 1 petaOPS, high energy efficiency (up to 20× performance per watt), 128GB LPDDR memory at 272Gbps, collaborations with TSMC, DARPA grants

41. Cognigy

Industry: AI / Conversational AI / Customer Service Automation

Cognigy provides a low-code enterprise platform (Cognigy.AI) for building, deploying, and managing AI agents for chat and voice customer service with multilingual, omnichannel support.

Location: Düsseldorf, Germany (global HQ); US HQ moved to Plano, TX, USA in April 2025
Founded: 2016
Last Funding Round: Series C, $100M (€93M), June 2024 (led by Eurazeo Growth)
Total Funding: ~$160M (including $59M Series B extension in 2022)
Valuation: Not publicly disclosed
Number of Users: Over 1,000 enterprise customers; thousands of AI Agents handling millions of conversations annually
Growth Rate: Revenue growth 828% since end of 2022; expanding U.S. headcount >100; scaling global deployments

Key Features

Low-code AI Agent Studio, conversational & generative AI agents, voice & chat support, multilingual (100+ languages), agent assist, deep backend integrations, SaaS or on-premise deployment, enterprise-grade scalability & compliance

42. Moonvalley

Industry: AI / Film / Creative Technology

Moonvalley specializes in generative video tools for filmmakers and creative professionals, with ethical, high-quality outputs and advanced cinematic controls.

Location: Los Angeles, CA, USA
Founded: 2024
Last Funding Round: $84M, July 2025 (part of multiple rounds totaling $154M)
Total Funding: $154M
Valuation: Not publicly disclosed
Number of Users: Not publicly disclosed
Growth Rate: Rapid funding growth; strong backing from General Catalyst and Khosla Ventures

Key Features

Generative video model Marey, pose transfer, camera & motion control, trajectory control, advanced lighting, high-resolution output, ethical training data using licensed content

43. XBOW

Industry: Cybersecurity AI / Offensive Security / Pentesting

XBOW offers an autonomous AI platform for continuous web application vulnerability detection and exploitation, outperforming top human penetration testers.

Location: Seattle, WA, USA
Founded: 2024
Last Funding Round: Series B, $75M, June 2025
Total Funding: $117M
Valuation: Not disclosed
Number of Users: Leading banks, tech firms, enterprises (Amazon, Disney, PayPal); #1 on HackerOne US
Growth Rate: Rapid adoption with top-ranked HackerOne performance; high enterprise sign-ups post-Series B

Key Features

Autonomous web vulnerability testing, continuous penetration, benchmark-beating ML models, automated exploit generation/validation, real-time security profiling

44. Nexthop AI

Industry: AI / Networking Hardware / Cloud Infrastructure

Nexthop AI provides custom networking hardware, optimized network operating systems, and pre-tested optical/electrical interconnects for hyperscale AI infrastructure and cloud providers.

Location: Santa Clara, CA, USA
Founded: 2024
Last Funding Round: Series A, $110M, March 2025
Total Funding: $110M
Valuation: Not publicly disclosed
Number of Users: Enterprise cloud providers and hyperscalers
Growth Rate: Rapid growth with strategic partnerships in hyperscale cloud & AI infrastructure

Key Features

Custom networking hardware, optimized network OS, pre-tested optical/electrical interconnects, scalable high-efficiency network solutions, collaboration with cloud providers

45. Eudia

Industry: AI / Legal Tech / Augmented Intelligence

Eudia offers an AI-powered augmented intelligence platform for Fortune 500 legal teams, automating workflows, surfacing insights, and combining AI with human expertise.

Location: Palo Alto, CA, USA
Founded: 2023
Last Funding Round: Series A, up to $105M, Feb 2025 (led by General Catalyst)
Total Funding: $105M
Valuation: Not publicly disclosed
Number of Users: Adopted by CLOs at Fortune 500 companies (Cargill, DHL, Duracell, Coherent)
Growth Rate: Over $10M ARR; on track for $20M by year-end; first acquisition (Johnson Hana) with $75M war chest

Key Features

Agentic AI platform, customized legal “brain” per enterprise, human-in-the-loop augmentation, document analysis, contract redlining, compliance automation, managed legal services via Johnson Hana acquisition

46. Graphite

Industry: AI Developer Tools / Code Review

Graphite is an AI-powered code review platform that automates feedback, summarizes pull requests, suggests improvements, and self-heals CI failures.

Location: New York, NY, USA
Founded: 2020
Last Funding Round: Series B, $52M, March 2025
Total Funding: $81M
Valuation: Not disclosed
Number of Users: Tens of thousands of engineers at over 500 companies, including Shopify, Snowflake, and Figma
Growth Rate: Revenue grew over 20× in 2024

Key Features

AI code review, pull request summarization, code suggestions, CI failure self-healing, customizable rules, GitHub integration, Diamond AI reviewer, Slack notifications, merge queue, reviewer assignment, productivity analytics

47. Bland

Industry: Conversational AI / Enterprise Automation / Voice AI

Bland provides AI-powered phone agents that automate inbound/outbound calls for enterprises with customizable voices and seamless integrations.

Location: San Francisco, CA, USA
Founded: 2023
Last Funding Round: $65M Series B, Jan 29, 2025
Total Funding: $65M
Valuation: Not publicly disclosed
Number of Users: Not publicly disclosed
Growth Rate: Rapid scaling from stealth to Series B in under 10 months

Key Features

Hyper-realistic AI voice agents, customizable voices, no-code workflow builder, real-time analytics, CRM integrations, multilingual support, 24/7 availability, ethical transparency

48. MindsDB

Industry: AI / Open Source / Developer Tools

MindsDB is an open-source AI data automation platform that lets developers build, deploy, and manage AI applications by unifying data and enabling natural-language querying without AI expertise.

Location: San Francisco, CA, USA
Founded: 2017
Last Funding Round: Series B, $25M led by Mayfield, June 2023
Total Funding: Over $50M
Valuation: Not publicly disclosed
Number of Users: Over 300,000 deployments; used by more than 100 startups and SMBs
Growth Rate: Revenue increased from $1.7M in 2021 to $5.3M in 2024; team of 37 employees

Key Features

Open-source and cloud-native AI platform, 200+ data integrations (Postgres, MongoDB, Snowflake, Salesforce), natural-language querying, model management, workflow automation tools, Model Context Protocol (federated data), enterprise-grade security

49. Coram AI

Industry: AI / Video Security / Surveillance

Coram AI offers an AI-powered video security platform that overlays “virtual security guards” on existing IP cameras for real-time threat detection, natural-language search, and safety alerts.

Location: Sunnyvale, CA, USA
Founded: 2022
Last Funding Round: Series A, $13.8M, January 2025 (led by Battery Ventures, with 8VC and Mosaic Ventures)
Total Funding: $30M
Valuation: Not publicly disclosed
Number of Users: Deployed across schools, hospitals, manufacturing and logistics sites; customers include Middletown USD and PCC Community Markets
Growth Rate: Rapid enterprise adoption; thousands of cameras active; strong VC interest

Key Features

Works with any IP camera, generative AI detection (firearms, slips, license plates, faces), natural-language video search, real-time alerts, cloud-based analytics

50. ListenLabs

Industry: AI-powered Customer Research

ListenLabs automates design, recruitment, conducting, and analysis of voice/video customer interviews, generating insights like reports, highlight reels, and presentations.

Location: San Francisco, CA, USA
Founded: 2023
Last Funding Round: Seed + Series A, $27M, April 2025
Total Funding: $27M
Valuation: Not disclosed
Number of Users: Hundreds of enterprises (Google, Microsoft, SKIMS, Nestlé, Canva, Chubbies)
Growth Rate: Over 300,000 interviews conducted by April 2025; rapid adoption

Key Features

AI-driven interview question design, participant sourcing, multilingual voice/video interviews, automatic theme extraction, video highlight reels, PPT presentations, real-time reports

Conclusion

What connects these companies isn’t just that they work in AI, it’s the scale of their ambition and the speed of their growth.

From infrastructure to creative tools, they’re not just adapting AI to existing industries, they’re building entirely new categories of technology.

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